ACTA MEDICA NAGASAKIENSIA seeks to provide a forum for the discussion of all aspects of medicine. We welcome original, unpublished papers for possible publication. In addition manuscripts that deal with case reports, short communications, and letters to the editor as well as review articles will be considered for publication. The guidelines for this journal are essentially in accordance with the "Uniform Requirements for Manuscripts Submitted to Biomedical Journals." (The complete document appears at

Editorial Policies
Submissions should be accompanied with the authors’ written confirmation that research contained in the manuscript has not been published and is not under consideration elsewhere. All authors listed on a manuscript should agree to its submission and content, as determined in the Uniform Requirements for Manuscripts Submitted to Biomedical Journals. All authors should also approve revisions to text or authors.
Editorial board members as well as a large group of external reviewers who have broad expertise in research areas of medicine shall provide fair and thorough evaluation of manuscripts submitted to ACTA MEDICA NAGASAKIENSIA. Editors and reviewers are expected to maintain a strict ethical code regarding confidentiality of the material under review.
Editorial board members and reviewers will disclose their conflict of interest that could inappropriately influence his or her judgment. Any relationships with a manuscript and participants in review will be revealed.
After review, authors will be promptly informed of editorial decisions. Manuscripts will not be returned. The copyright for articles that have been accepted in this journal shall be transferred from authors to the Editorial Board of ACTA MEDICA NAGASAKIENSIA. The form of copyright transfer will be sent to the corresponding author with galley proofs.

Submission of Manuscripts
Authors should send two copies of the manuscript (the original and photocopy) and two sets of figures to:
Masataka Uetani, MD
Department of Radiological Science, Nagasaki University Graduate School of Biomedical Sciences
1-7-1 Sakamoto, Nagasaki 852-8501 Japan
FAX: +81 (0)95 819 7357

Manuscript preparation
The manuscript should be submitted with a cover letter stating:
(1) That the manuscript is being submitted for consideration for publication in ACTA MEDICA NAGASAKIENSIA. Please specify the category of the submitted manuscript.
(2) That the manuscript has not been published or is not under consideration for publication elsewhere.
(3) That all authors have read and approved the content and the authorship of the submitted manuscript.

Format and Style
Manuscripts should be written in clear and grammatically correct English. The manuscripts that are not in the style of ACTA MEDICA NAGASAKI ENSIA or not in good idiomatic English will be returned to the author without being reviewed. When manuscript is written by authors whose first language is not English, it should be checked by an editing service with native scientists. Terminology and abbreviations not consistent with internationally accepted guidelines should be avoided. The manuscript should be typed double-spaced on one side only of A4 size paper (210_297 mm) throughout including tables and figure legends with generous margins. Numbering of lines in the margin is desirable to facilitate the review. Consecutive numbering of all pages is required, with the title page as page 1. The manuscript should follow the order starting as a new page: (a) title page, (b) abstract, (c) text (introduction, materials and methods, results and discussion), (d) acknowledgments, (e) references, (f) tables, (g) figure legends, and (h) figures. Abbreviations for scientific units must confirm to the System International (SI units). Please note that footnotes are not allowed.

Title Page
Title: The title should be informative and brief.
Names and Affiliations of Authors: Full names (first name, middle name and last name) and affiliations (names of institutions and subsidiary laboratories or departments, city and country) should be described for all authors. The name, complete address including postal code, telephone and fax numbers, and an e-mail address should be described for the corresponding author.
Running Title: A brief running title not exceeding 50 characters including spaces) should be provided.

The abstract should be no more than 250 words and indicate the content of the manuscript. All important terms relevant to the content of the manuscript should be incorporated in the abstract. Abbreviations should be kept to an absolute minimum; however, if they are needed, they should be defined in both the abstract and the text so that the abstract can be viewed independently of the text. Follow this with up to six key words or short phrases for indexing.

It is usual but not essential to organize the text under the following headings.
Introduction: State why the investigation was carried out, note any relevant published work and delineate the objectives of the investigation. The significance of the work and its contribution to the area of study should be stated.
Materials and Methods: The methods should be briefly but clearly explained. Procedures published previously need only be cited as references. New and significant modifications need complete exposition. When reporting study on human subjects, indicate whether the procedures followed were in accordance with the ethical standards. When reporting experiments on animals, indicate the institution’s or a national research councils guidelines for, or any national law on, the care and use of laboratory animals. Describe statistical methods with enough detail to enable a knowledgeable reader with access to the original data to verify the reported results. When possible, quantify findings and present them with appropriate indicators of measurement error or uncertainty (such as confidence intervals). Avoid relying solely on statistical hypothesis testing, such as the use of p-values, which fails to convey important quantitative information.
Results: The findings of the study should be concisely summarized. Textual description of the data must be presented in tables and figures, and duplication between the text of this section and material presented in tables and figures should be avoided.
Discussion: The discussion section should emphasize the major findings of the study and its significance to existent knowledge. Information presented in the previous section should not be repeated. Concise interpretation of the data with well-founded speculation should be included.

Authors are responsible for recognizing and disclosing financial and other conflicts of interest that might bias their work. They should acknowledge in the manuscript all financial support for the work and other financial or personal connections to the work.

Number references in the order they are mentioned in the text; do not alphabetize. In text, tables and legends, identify references with superscript Arabic numerals. The reference list should be arranged in the order of citation. List all authors when six or less; for seven or more authors, list the first three followed by et al. Journal titles should be abbreviated according to the latest edition of Index Medicus, if applicable. Here are some examples:
1) Zea-Iriete WL, Makiyama K, Goto S et al. Significance of impairment of antioxidants in colonic epithelial cells isolated from TNBS-induced colitis rats. Acta Med Nagasaki 41: 35-42, 1996
2) Maruyama Y, van Nagell JR. Radiation therapy for cervical cancer. In Modern Concepts of Gynecologic Oncology (van Nagell JR, Barder HJ eds.; Wright-PSG Publishers, Boston) pp. 91-158, 1982

Tables should be numbered and cited in numerical order in the text, and each should be on a separate page, numbered in sequence in Arabic numerals (Table 1, 2, etc.), provided with a heading, and referred to in the text as Table 1, Table 2, etc. Explanations sufficient to make the data intelligible without reference to the text must be typed below the table on the same page.

Figures should be numbered in Arabic numerals according to the sequence of their appearance in the text, where they are referred to as Figure 1, Figure 2, etc. The name of the first author, the figure number should be written at the corner of each figure. In case of pictures, designation of the top of the picture figure should be clearly indicated. Line drawings may be submitted either as printout from a laser printer or in camera-ready form on a white background.

Figure Legends
Figure legends should be on a separate page, and should include a brief title and a concise explanation of each figure.

Page and Other Charges
There will be a charge of JPY 3,000 (ca USD 25) per printed page in the journal.
There will be additional charges for color illustrations, as well as excessive or other unusual illustrative material.
In extraordinary cases, on appeal by the author, the Editorial Board may waive the page or other charges.

Electronic Manuscript
Upon acceptance, the final version should be submitted on a 3.5-inch diskette in addition to the printout. Whenever possible, please submit your text on a diskette formatted for DOS. If possible, please store your text in two versions: 1. In the standard data file format offered by your word processing system; 2. In one of the data interchange file format MS-DOS Text. Specify what software was used, including release, e.g., Microsoft Word 6.0, and what computer was used (Apple Macintosh, IBM compatible PC, etc.). The article file should include all textual material (text, references, tables, figure legends, etc.) and separate illustration files, if available. The diskette must correspond exactly with the final printout sent to the Editor-in-Chief. Keep a back-up disk for reference and safety.

Galley Proofs
Galley Proofs will be sent to the corresponding author. Changes in the manuscript will not be allowed except printing errors. The corrected galley proofs should be returned within 48 hours after receipt.

Thirty reprints are offered free of charge. Additional reprints may be ordered at prices shown in the reprint order form, which will be sent to the corresponding author with galley proofs.

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