業績

HOME＞業績＞2008年（平成20）業績
２００８年（平成２０）業績

（英文）

  1. Seki M, Higashiyama Y, Imamura Y, Nakamura S, Kurihara S, Izumikawa K, Kakeya H, Yamamoto Y, Yanagihara K, Tashiro T, Kohno S. A clinical comparative study of piperacillin and sulbactam/ampicillin in patients with community-acquired bacterial pneumonia. Intern Med 48:49-55,2008
  2. Seki M, Suyama N, Hashiguchi K, Hara A, Kosai K, Yanagihara K, Nakamura S, Kurihara S, Imamura Y, Izumikawa K, Kakeya H, Yamamoto Y, Mukae H, Tashiro T, Kohno S. A patient with fulminant influenza-related bacterial pneumonia due to Streptococcus pneumoniae followed by Mycobacterium tuberculosis infection Intern Med 47:2043-2047,2008
  3. Kosai K, Seki M, Yanagihara K, Nakamura S, Kurihara S, Imamura Y, Izumikawa K, Kakeya H, Yamamoto Y, Tashiro T, Kohno S. Two-dimensional gel electrophoresis analysis in simultaneous influenza pneumonia and bacterial infection in mice. Clin Exp Immunol. 152:364-371,2008
  4. Morinaga Y, Yanagihara K, Nakamura S, Yamamoto K, Izumikawa K, Seki M, Kakeya H, Yamamoto Y, Yamada Y, Kohno S, Kamihira S. In vivo efficacy and pharmacokinetics of tomopenem（CS-023）, a novel carbapenem, against Pseudomonas aeruginosa in a murine chronic respiratory tract infection model. J Antimicrob Chemother 62:1326-1331,2008
  5. Yanagihara K, Ohnishi Y, Morinaga Y, Nakamura S, Kurihara S, Seki M, Izumikawa K, Kakeya H, Yamamoto Y, Yamada Y, Kamihira S, Kohno S. Efficacy of ME1036 against methicillin-resistant Staphylococcus aureus and vancomycin-insensitive S. aureus in a model of hematogenous pulmonary infection. Int J Antimicrob Agents 32:401-404,2008
  6. Kosai K, Seki M, Yanagihara K, Nakamura S, Kurihara S, Izumikawa K, Kakeya H, Yamamoto Y, Tashiro T, Kohno S: Elevated levels of high mobility group box chromosomal protein-1（HMGB-1）in sera from patients with severe bacterial pneumonia coinfected with influenza virus. Scand J Infect Dis 40:338-342,2008
  7. Kosai K, Seki M, Yanagihara K, Nakamura S, Kurihara S, Izumikawa K, Kakeya H, Yamamoto Y, Tashiro T, Kohno S: Gabexate mesilate suppresses influenza pneumonia in mice through inhibition of cytokines. J Int Med Res 36:322-328,2008
  8. Kakeya H, Miyazaki Y, Senda H, Kobayashi T, Seki M, Izumikawa K, Yamamoto Y, Yanagihara K, Tashiro T, Kohno S: Efficacy of SPK-843, a novel polyene antifungal, in a murine model of systemic cryptococcosis. Antimicrob Agents Chemother. 52:1871-1872,2008
  9. Kakeya H, Miyazaki Y, Kobayashi T, Seki M, Izumikawa K, Yanagihara K, Yamamoto Y, Tashiro T, Kohno S: Efficacy of SPK-843, a novel polyene antifungal, in comparison with amphotericin B, liposomal amphotericin B, and micafungin against murine pulmonary aspergillosis. Antimicrob Agents Chemother. 52:1868-1870,2008
  10. Kakeya H, Ehara N, Fukushima K, Seki M, Izumikawa K, Yamamoto Y, Yanagihara K, Saito A, Kohno S: Severe legionnaires' disease successfully treated using a combination of fluoroquinolone, erythromycin, corticosteroid, and sivelestat. Intern Med 47:773-777,2008
  11. Yanagihara K, Morinaga Y, Nakamura S, Seki M, Izumikawa K, Kakeya H, Yamamoto Y, Kohno S: Subinhibitory concentrations of telithromycin, clarithromycin and azithromycin reduce methicillion-resistant Staphylococcus aureus coagulase in vitro and in vivo. J Antimicrob Chemother 61:647-650,2008
  12. Kihara R, Yanagihara K, Morinaga Y, Araki N, Nakamura S, Seki M, Izumikawa K, Kakeya H, Yamamoto Y, Tsukamoto K, Kamihira S, Kohno S: Potency of SMP-601, a novel carbapenem, in hematogenous murine bronchopneumonia caused by methicillin-resistant and vancomycin-intermediate Staphylococcus aureus. Antimicrob Agents Chemother 52:2163-2168,2008
  13. Hirakata Y, Yanagihara K, Kurihara S, Izumikawa K, Seki M, Miyazaki Y, Kohno S: Comparison of usefulness of plasma procalcitonin and C-reactive protein measurements for estimation of severity in adults with community-acquired pneumonia. Diagn Microbiol Infect Dis 61:170-174,2008
  14. Tashiro M, Izumikawa K, Yoshioka D, Nakamura S, Kurihara S, Sakamoto N, Seki M, Kakeya H, Yamamoto Y, Yanagihara K, Mukae H, Hayashi T, Fukushima K, Tashiro T, Kohno S: Lung fibrosis 10 years after cessation of bleomycin therapy. Tohoku J Exp Med 216:77-80,2008
  15. Yamamoto Y, Shioshita K, Takazono T, Seki M, Izumikawa K, Kakeya H, Yanagihara K, Tashiro T, Otsuka Y, Ohkusu K, Kohno S: An autopsy case of Erysipelothrix rhusiopathiae endocarditis. Intern Med 47:1437-1440,2008
  16. Saijo T, Izumikawa K, Takazono T, Kosai K, Kurihara S, Nakamura S, Imamura Y, Miyazaki T, Seki M, Kakeya H, Yamamoto Y, Yanagihara K, Miyazaki Y, Fukushima K, Kohno S: A case of Legionella pneumophila pneumonia followed by invasive aspergillosis. Jpn J Infect Dis 61:379-381,2008
  17. Izumikawa K, Zhao Y, Motoshima K, Takazono T, Saijo T, Kurihara S, Nakamura S, Miyazaki T, Seki M, Kakeya H, Yamamoto Y, Yanagihara K, Miyazaki Y, Hayashi T, Kohno S: A case of pulmonary cryptococcosis followed by pleuritis in an apparently immunocompetent patient during fluconazole treatment. Med Mycol 46:595-599,2008
  18. Nakamura S, Higashiyama Y, Izumikawa K, Seki M, Kakeya H, Yamamoto Y, Yanagihara K, Miyazaki Y, Mizuta Y, Kohno S: The roles of the quorum-sensing system in the release of extracellular DNA, lipopolysaccharide, and membrane vesicles from Pseudomonas aeruginosa. Jpn J Infect Dis 61:375-378,2008
  19. Nakamura S, Izumikawa K, Seki M, Kakeya H, Yamamoto Y, Yanagihara K, Miyazaki Y, Kohno S: Pulmonary Cryptococcosis in Late Pregnancy and Review of Published Literature. Mycopathologia 167:125-131,2008
  20. Nakamura S, Yanagihara K, Izumikawa K, Seki M, Kakeya H, Yamamoto Y, Kohno S: A 52-year-old male with Fever and rapidly progressive dyspnea. Respiration 76:454-457,2008
  21. Nakamura S, Yanagihara K, Izumikawa K, Seki M, Kakeya H, Yamamoto Y, Miyazaki Y, Suyama N, Kohno S: Severe pulmonary tuberculosis complicating Ileocecal intussusception due to intestinal tuberculosis: a case report. Ann Clin Microbiol Antimicrob 7:16,2008
  22. Nakamura S, Izumikawa K, Seki M, Fujimoto K, Mishima K, Kakeya H, Yamamoto Y, Yanagihara K, Mizuta Y, Kitaoka T, Kohno S: Reversible visual disturbance due to cryptococcal uveitis in a non-HIV individual. Med Mycol 46: 367-70,2008
  23. Nakamura S, Yanagihara K, Izumikawa K, Seki M, Kakeya H, Yamamoto Y, Soejima Y, Mizuta Y, Kohno S. Systemic metastatic infection and multiple brain abscesses due to severe Klebsiella pneumoniae infection in a 61-year-old male: A case report. IMEID 1:CS1-4,2009

（和文）

  1. 近藤　彰、原　耕平、泉川欣一、泉川公一、河野　茂：【症例】短期間で発症した慢性好酸球性肺炎の１例．呼吸 27:415-419、2008
  2. 平泻洋一、栁原克紀、松田淳一、泉川公一、山口敏行、竹村　弘、田中宏典、吉田良滋、青木志保、近藤　晃、山本和子、賀来満夫、山口惠三、河野　茂：長崎大学医学部・歯学部附属病院検査部におけるメタロ−β−ラクタマーゼの検出法と1991年から2005年の15年間におけるメタロ−β−ラクタマーゼ産生菌の分離状況．感染症学雑誌 82:285-291、2008
  3. 中村茂樹、栁原克紀、三原　智、泉川公一、関　雅文、掛屋　弘、山本善裕、副島佳文、田代隆良、河野　茂：当院における超高齢者肺炎34例の臨床的検討．日本呼吸器学会雑誌 46:687-691、2008 
  4. 中村茂樹、栁原克紀、泉川公一、関　雅文、掛屋　弘、山本善裕、迎　寛、田代隆良、河野　茂：重症肺炎に伴う急性肺障害に対するシベレスタットナトリウム（エラスポール）の有用性の検討．日本呼吸器学会雑誌 46:793-797、2008
  5. 田代将人、福島喜代康、原　敦子、江原尚美、掛屋　弘、齊藤　厚、河野　茂：日米のガイドラインに基づく市中肺炎の重症度の検討．日呼吸会誌 46:981-985、2008
  6. （総監訳）河野　茂、（監訳）掛屋　弘、泉川公一：アスペルギルス症の治療：米国感染症学会臨床治療ガイドライン．Clin Infect Dis 46:327-360、2008
  7. 河野　茂、小川晴彦、松瀬厚人、泉川公一：呼吸器領域における真菌の関与．深在性真菌症 4:60-71、2008
  8. 泉川公一、河野　茂：真菌症に挑む・内科領域の深在性真菌症．日本医真菌学会雑誌49:275-280、2008
  9. 泉川公一：１　感染症呼吸器疾患　Ａ．細菌感染症　嫌気性菌肺炎．別冊日本臨牀　新領域別症候群シリーズ 8:169-171、2008
  10. 泉川公一、河野　茂：呼吸器領域における真菌の関与　呼吸器内科における深在性真菌症（特に治療について）　深在性真菌症〜SFI Forum〜 4:69-71、2008
  11. 今村圭文、泉川公一、河野　茂: ガンジダ症．日本臨牀 66:2341-2344、2008
  12. 泉川公一、山本善裕：のどの痛みを訴えられたら．（河野　茂、早田　宏（編）：レジデントのための呼吸器診療マニュアル、医学書院、東京、pp.37-43所収）2008
  13. 中村茂樹、栁原克紀：市中肺炎；何を選んでどう使うか？．（渡辺　彰　編）：モダンフィジシャン、新興医学出版社、東京、pp.1323-1328、20008
  14. 中村茂樹、河野　茂：肺真菌症の画像診断と治療．（藤田次郎　編）：肺炎の画像診断と最新の治療、医薬ジャーナル社、東京、pp301-305、2008

（学会発表）

  1. ATS 2008（トロント）Kohno S, Izumikawa K, Akamatsu S, Kageyama A, Takayanagi N, Nakamura S, Inoue Y, Higashiyama Y, Fukushima K, Ishida T,  Sawai T, Yoshimura K, Nakahama C, Omichi M, Kakukawa T, Nishioka Y, Aoki N, Seki M, Kakeya H, Yamamoto Y, Yanagihara K: Evaluation of a rapid immunochromatographic ODK0501 assay for detecting Streptococcus pneumoniae antigens in sputum from patients with lower respiratory tract infection
  2. 17th International Congress for Tropical Medicine and Malaria（済州島）Kakeya H, Yamamoto Y, Saijo T, Izumikawa K, Seki M, Yanagihara K, Kohno S: Case report: The severe Plasmodium falciparum malaria with acute renal failure and pancreatitis
  3. 48th Interscience Conference on Antimicrobial Agents and Chemotherapy Washington DC（ワシントン）Yanagihara K,  Morinaga Y, Araki N, Nakamura S, Izumikawa K, Seki M, Kakeya H, Yamamoto Y, Kamihira S, Kohno S: In vivo efficacy of sivelestat in combination with pazufloxacin against legionella pneumphila in a murine pneumonia model
  4. 48th Interscience Conference on Antimicrobial Agents and Chemotherapy Washington DC（ワシントン）Yanagihara K,  Araki N, Morinaga Y, Nakamura S, Seki M, Izumikawa K,  Kakeya H, Yamamoto Y, Kamihira S, Kohno S: In vivo efficacy of doripenem（s-4661）, a novel carbapenem, against Pseudomonas aeruginosa in a murine chronic respiratory tract infection model
  5. 11th Western Pacific Congress on Chemotherapy and Infectious Diseases 2008（タイペイ）Nakamura S, Yanagihara K, Morinaga Y, Izumikawa K, Seki M, Kakeya H, Yamamoto Y, and Kohno S: In vitro activity of sitafloxacin against Haemophilus influenzae including clinical isolates of fluoroquinolone-resisitant strains, and comparison of its mutant prevention concentration to levofloxacin, garenoxacin and ciprofloxacin
  6. 108th General Meeting of the American Society for Microbiology（ボストン）Nakamura S, Yanagihara K, Morinaga Y, Izumikawa K, Seki M, Kakeya H, Yamamoto Y, Kohno S: Clinical Impact of Multiplex Real-time PCR for Rapid Detection of β-lactamase negative ampicillin resistant Haemophilus influenzae（BLNAR）
  7. 108th General Meeting of the American Society for Microbiology（ボストン）Takazono T, Izumikawa K, Kosai K, Saijo T, Nakamura S, Kurihara S, Yamamoto K, Kobayashi T, Imamura Y, Miyazaki T, Seki M, Kakeya H, Yamamoto Y, Yanagihara K, Tashiro T, Kohn S: Analysis of pseudo-positive factors of PlateliaTM Aspergillus galactomannan antigen detection kit in respiratory tract infection patients
  8. 108th General Meeting of the American Society for Microbiology（ボストン）K. Yamamoto, K. Yanagihara, Y. Morinaga, K. Izumikawa, M. Seki, H. Kakeya, Y. Yamamoto, S. Kamihira, S. Kohno: In vitro Activitiy of Garenoxacin against Streptococcus pneumoniae Mutants with Characterized Resistance Mechanisms
  9. Pacific Rim Airway Mucus Symposium, 2008（ソウル）Morinaga Y, Yanagihara K, Miyashita N, Izumikawa K, Seki M, Kakeya H, Yamamoto Y, Yamada Y, Kamihira S, Kohno S: Azithromycin, Clarithromycin and Telithromycin Inhibit MUC5AC Production Induced by Chlamydophila pneumoniae Protein in NCI-H292 Cells
  10. 108th General Meeting of the American Society for Microbiology（ボストン）Morinaga Y, Yanagihara K, Miyashita N, Nakamura S, Izumikawa K, Seki M, Kakeya H, Yamamoto Y, Yamada Y, Kohno S, Kamihira S: Azithromycin, Clarithromycin and Telithromycin Inhibit MUC5AC Production Induced by Chlamydophila pneumoniae Protein in NCI-H292 Cells
  11. ATS 2008（トロント）Seki M, Kosai K, Yanagihara K, Kurihara S, Izumikawa K, Kakeya H, Yamamoto Y, Tashiro T, and Kohno S: Two-dimensional gel electrophoresis analysis in simultaneous influenza pneumonia and bacterial infection in mice
  12. 13th Congress of the Asian Pacific Society of Respirology（バンコク）Hirano K, Kakeya H, Mihara T, Yamamoto K, Imamura Y, Seki M, Izumikawa K, Yanagihara K, Yamamoto Y, Mine M, Tashiro T, Kohno S: The Clinical Feature of Pulmonary Cryptococcosis without HIV Infection in Nagasaki
  13. 13th Congress of the Asian Pacific Society of Respirology（バンコク）Iwanaga N, Yamamoto K, Minematsu A, Hirano K, Imamura Y, Izumikawa K, Seki M, Kakeya H, Yamamoto Y, Yanagihara K, Kohno S: Use of Quanti FERON TB-2G Test for the Diagnosis of Tuberculosis Infection in Nagasaki University Hospital.
  14. 第82回　日本感染症学会総会（松江）（ミニ特別講演）泉川公一：「私たちの研究は　今　肺真菌症の診断と治療」
  15. 第48回　日本呼吸器学会総会（神戸）（イブニングシンポジウム）泉川公一：「呼吸器内科における深在性真菌症（特に治療について）」
  16. 第52回　日本医真菌学会総会（長崎）（シンポジウム）泉川公一：「The Frontline of Respiratory Fungal Infections in JAPAN」
  17. 第55回　日本化学療法学会東日本地方会（埼玉）（教育セミナー）泉川公一：「市中肺炎における注射用ニューキノロン系薬」
  18. 第56回　日本化学療法学会西日本支部総会・第78回日本感染症学会西日本支部総会（広島）（合同シンポジウム）泉川公一：「感染制御の新時代に向けて：—基礎・臨床・コメディカルのパートナーシップ—　真菌へのアプローチ」