業績

2019年 業績
  1. S Nakamae, D Kimura, M Miyakoda, O Skhbaatar, S Inoue, K Yui. Role of IL-10 in inhibiting protective immune responses against infection with heterologous Plasmodium parasites. Parasitol Int, 70: 5-15, 2019.
2018年 業績
  1. C Kijogi, D Kimura, LQ Bao, R Nakamura, E A Chadeka, N B Cheruiyot, F Bahati, K Yahata, O Kaneko, S M. Njenga, Y Ichinose, S Hamano, K Yui, Modulation of immune responses by Plasmodium falciparum infection in asymptomatic children living in the endemic region of Mbita, western Kenya. Parasit Int, 67; 284-293, 2018.
  2. M Akbari, K Kinura, G Bayarsaikhan, D Kimura, M Miyakoda, S Juriasingani, M Yuda, R Amino, K Yui. Non-specific CD8+ T cells and dendritic cells/macrophages particilate formation of CD8+ T cell-mediated clusters against malaria liver-stage infection. Infect Immun, 86 (4) pii: e00717-17, doi: 10.1128/IAI.00717-17. 2018.
  3. K Ochiai, H Kondo, Y Okamura, H Shima, Y Kurokochi, K Kimura, R. Funayama, T Nagashima, K Nakayama, K Yui, K Kinoshita, K Igarashi, Zinc-finger-IRF composite elements bound by Ikaros/IRF4 complex functions as gene repression in plasma cell, Blood Adv., 2 (8); 883-894, 2018.
  4. M Miyakoda, K Honma, D Kimura, M. Akbari, K Kimura, T Matsuyama, K Yui, Differential requirements for IRF4 in the clonal expansion and homeostatic proliferation of naïve and memory murine CD8+ T cells, Eur J Immunol., 48: 1319-1328, 2018.
  5. K Maeda, M Yoneda, T Nakagawa, K Ikeda, M Higashi, K Nakagawa, M Miyakoda, K Yui, H Oda, S Inoue, T Ito, Defects in centromeric and pericentromeric histone H2A T120 phosphorylation by hBUB1 cause missegregation, resulting in multinucleated cells, Genes to Cells, 23: 828-838, 2018.
  6. Lauren E Holz, Julia Prier, David Freestone, Thaigo Maass Steiner, Kieran English, Darryl N. Johnson, Vanessa Mollard, Anton Cozijnsen, Gayle M. Davey, Dale I Godfrey, Katsuyuki Yui, Laura K Mackay, Irina Caminschi, Geoffrey I. McFadden, Patrick Bertolino, Daniel Fernandez-Ruiz and William R. Heath. CD8+ T cell activation leads to constitutive formation of liver tissue-resident memory T cells that seed a large and flexible niche within the liver. Cell reports, 25: 68-79, 2018.
  7. M Miyakoda, B Ganchimeg, D Kimura, M. Akbari, H Udono, K Yui, Metformin promotes protection of mice infected with Plasmodium yoelii independently of γδ T cell expansion, Front Immunol, 9:2942. 2018.
2017年 業績
  1. Bayarsaikhan G, Miyakoda M, Yamamoto K, Kimura D, Akbari M, Yuda M, Yui K. Activation and exhaustion of antigen-specific CD8+ T cells occur in different splenic compartments during infection with Plasmodium berghei. Parasitol Int. 66(3):227-235. 2017.
  2. Saito Y, Respatika D , Komori S, Washio K, Nishimura T, Kotani T, Murata Y, Okazawa H, Ohnishi H, Kaneko Y , Yui K, Yasutomo K, Nishigori C, Nojima Y, Matozaki T. SIRPa+ dendritic cells regulate homeostasis of fibroblastic reticular cells via TNF receptor ligands in the adult spleen. Proc. Natl Acad Sci (USA). 114 (47): E10151-E10160. 2017
  3. Fuchigami T, Ono H, Oyadomari K, Iwatake M, Hayasaka D, Akbari M, Yui K, Nishi K, Kudo T, Yoshida S, Haratake Mamoru , and Nakayama M. Development of a 68Ge/68Ga Generator System Using Polysaccharide Polymers and Its Application in PET Imaging of Tropical Infectious Diseases. ACS OMEGA. 2:1400-1407¸2017
2016年 業績
  1. Kimura D, Miyakoda M, Kimura K, Honma K, Hara H, Yoshida H, Yui K. Interleukin-27-producing CD4+ T cells regulate protective immunity during malaria parasite infection. Immunity. 44(3):672-682. 2016.
  2. Akbari M, Kimura K, Houts JT, Yui K. Intravital imaging of the immune responses during liver-stage malaria infection: an improved approach for fixing the liver. Parasitol Int. 65(5):502-505. 2016
  3. Dang M N, Huy N, Ohyama K, Kimura D, Lan N, Uchida L, Thuong N, Nhon C, Phuc L, Mai N, Mizukami S, Bao L, Doan N, Binh N, Quang L, Karbwang J, Yui K, Morita K, Huong V, Hirayama K. A Proteomic Approach identifies candidate early Biomarkers to Predict Severe Dengue in Children. PLOS Negl Trop Dis. 19;10(2):e0004435. 2016.
  4. Doe T.H, Kimura D, Miyakoda M, Kimura K, Akbari M, Yui K. Expression of PD-1/LAG-3 and cytokine production by CD4+ T cells during infection with Plasmodium parasites. Microbiol Immunol. 60(2):121-131. 2016.
  5. Inamura Y, Honma K, Kimura D, Miyakoda M, Kimura K, Fukudome K, Nanashima A, Nagayasu T, K Yui, Recruitment of distinct immune cell populations to the lung after intractracheal TLR4 signaling activation by two different stimulations, Acta Med Nagasaki, 60(2):77-84. 2016.
2015年 業績
  1. Tamura T, Kimura K, Yui K, Yoshida S. Reduction of conventional dendritic cells during Plasmodium infection is dependent on activation induced death by type I and II interferons, Exp Parasitol, 159:127-135, 2015.
  2. Akazawa S, Kobayashi M, Kuriya G, Yu L, Kawasaki E, Yamasaki H, Nagayama Y, Matsuyama M, Akbari M, Yui K, Kawakami A, Abiru N. Haplotype infufficiency of interferon regulatory factor 4 strongly protects against autoimmune in non-obese diabetic mice, Diabetologia, 58: 2606-2614, 2015.
  3. Bayarsaikhan G, Akbari M, Yui K, Amino R. Antigen-driven focal inflammatory death of malaria liver stages, Front Microbiol, doi: 10.3389/fmicb.2015.00047 eb, 2015
2014年 業績
  1. Akbari M, Honma K, Kimura D, Miyakoda M, Kimura K, Matsuyama T, Yui K. IRF4 in dendritic cells inhibits IL-12 and controls Th1 immune responses against Leishmania major.J. Immunol., 192 (5): 2271-2279.  2014.
  2. Tamura T, Akbari M, Kimura K, Kimura D, Yui K. Flt3 ligand treatment modulates rodent parasitemia infection via MyD88 and IFN-g-dependent mechanisms.  Parasite Immunol. 36: 87-99, 2014.
  3. Cherif MS, Shuaibu MN, Kodama Y, Kurosaki T, Helegbe GK, Kikuchi M, Ichinose A, Yanagi T, Sasaki H, Yui K, Tien NH, Karbwang J, Hirayama K. Nanoparticle formulation enhanced protective immunity provoked by PYGPI8p-transamidase related protein (PyTAM) DNA vaccine in Plasmodium yoelii malaria model.  Vaccine, 32 (17): 1998-2006, 2014.
  4. Nakamura S, Kondo N, Yamaguchi Y, Hashiguchi M, Tanabe K, Ushiroda C, Kawahashi- Tokuhisa M, Yui K, Miyakoda M, Oku T. Daily feeding of fructooligosaccharide or glucomannan delays onset of senescence in SAMP8 mice, Gastroenterol. Res. Pract., ID 303184, 2014.
  5. Mac-Daniel L, Buckwalter M, Berthet M, Virk Y, Yui K, Albert M, Gueirard P, Ménard R.  Local immune response to injection of Plasmodium sporozoites into the skin. J. Immunol. 193: 1246-1257, 2014.
2013年 業績
  1. Kimura K, Kimura D, Matsushima Y, Miyakoda M, Honma K, Yuda M, Yui K. CD8+ T cells specific for a malaria cytoplasmic antigen form clusters around infected hepatocytes and are protective at the liver stage of infection. Infect Immun. 81(10):3825-3834. 2013.
  2. Kamei R, Miyakoda M, Tamura T, Kimura D, Honma K, Kimura K, Yui K. Accumulation of major histocompatibility complex class II+CD11c- non-lymphoid cells in the spleen during infection with Plasmodium yoelii is lymphocyte-dependent. Microbiol Immunol. 57:213-223. 2013.
  3. K. Yui, Closeup: Cross-presentation of malaria antigen by brain microvessels: why CD8+ T cells are critical for the pathogeneisis of cerebral malaria.  EMBO Mol. Med. 5 (7):899-901、2013.
  4. Bao, L.Q., Huy, N.T., Kikuchi, M., Yanagi, T., Senba, M., Shuaibu, M.N., Honma, K., Yui, K., Hirayama, K.,  CD19(+) B cells confer protection against experimental cerebral malaria in semi-immune rodent model., PLos One, May 28;8(5):e64836, 2013.
  5. Tamiya, T, Ichiyama, K, Kotani, H, Fukaya, T, Sekiya T, Shichita, T, Honma, K, Yui, K, Matsuyama, T, Nakao, T, Fukuyama, S, Inoue, H, Nomura, M, Yoshimura, A. Smad2/3 and IRF4 play a cooperative role in Interleukin-9-producing T cell induction,  J. Immunol., 191 (9) : 2360-2371, 2013.
  6. Kurosaki T, Kodama Y, Muro T, Higuchi N, Nakamura T, Kitahara T, Miyakoda M, Yui K, Sasaki H. Secure splenic delivery of plasmid DNA and its application to DNA vaccine. Biol Pharm Bull. 36(11):1800-6. 2013.
2012年 業績
  1. Okamoto K, Kinoshita H, del Camen Parquet M, Rawekiensya M, Kimura D, Yui K, Alimul Islam M, Hasebe F, Morita K. DEN2 16681 strain utilizes specific glycochain of Syndecan-2 proteoglycan as a receptor. J. Gen. Virol., 93:761-770. 2012.
  2. Chapman LM, Aggrey AA, Field DJ, Srivastava K, Ture S, Yui K, Topham DJ, Baldwin III WM, Morell CN. Platelets presents antigen in the context of MHC class I. J. Immunol., 189 (2):916-923. 2012.
  3. Inoue M, Jianxia T, Miyakoda M, Kaneko O, Yui, K, Culleton R. The species specificity of immunity generated by live whole organism immunization with erythrocytic and pre-erythrocytic stages of rodent malaria parasites and implications for vaccine development. Int. J. Parasitol., 42:859-870. 2012.
  4. Miyakoda M, Kimura D, Honma K, Kimura K, Yuda M, Yui K. Development of memory CD8+ T cells and their recall responses during blood-stage infection with Plasmodium berghei ANKA. J. Immunol.,189(9):4396-4404. 2012.
  5. Ito S, Nagata Y, Susumu S, Yoneda A, Matsuo M, Yui K, Udono H, Eguchi S, Kanematsu T. Phenotypic analysis of monocyte-derived dendritic cells loaded with tumor antigen with heat-shock cognate protein-70. Anticancer Res. 32 (11): 4897-4904. 2012.
2011年 業績
  1. Taguchi T, Inamura Y, Honma K, Kimura D, Miyakoda M, Miyazaki T, Tsuchiya T, Yamasaki N, Tagawa T, Nagayasu T, Yui K. Characterization of waves of leukocyterecruitment to the lung allograft and the effect of CTLA4-Ig, Acta Medica Nagasakientia. 56:27-34. 2011.
  2. Shindo H, Yasui K, Yamamoto K, Honma K, Yui K, Kohno T, Yuhua Ma Y Chua Koon Jiew, Kubo Y, Aihara H, Ito T, Nagayasu T, Matsuyama T, Hayashi H. Interferonregulatory factor-4 activates IL-2 and IL-4 promoters in cooperation with c-Rel. Cytokine. 56 (3):564-572. 2011.
  3. Tamura T, Kimura K, Yuda M Yui K. Prevention of experimental cerebral malaria by Flt3 ligand during infection with Plasmodium berghei ANKA. Infect Immun, 79(10): 3947-3956. 2011.
2010年業績
  1. Kimura D, Miyakoda M, Honma K, Yuda M, Chinzei Y, Yui K.  Production of IFN-g by CD4+ T cells in response to malaria antigens is IL-2-dependent. Int. Immunol. 22 (12):941-952. 2010.
  2. Satoh T, Takeuchi O, Vnadenbon A, Yasuda K, Tanaka Y, Kumagai Y, Miyake T, Matsushita K, Okazaki T, Saitoh T, Honma K, Matsuyama T, Yui K, Tsujimura T, Standley D.M., Nakanishi K, Nakai K, Akira S. The JMJD3-IRF4 axis regulates M2 macrophage polarization and host response against helminth infection. Nature Immunol. 11 (10): 936-944. 2010.
  3. Inoue M, Tang J, Kaneko O, Yui K, Culleton R. Complete abrogation of sporozoite-induced sterile immunity by blood stage parasites of homologous and heterologous malaria parasites. Malaria J. 9 (suppl)O19. 2010.
2009年 業績
  1. Lee C-G, Kang K-H, So J-S, Kwon H-K, Son J-S, Song M-K, Sahoo A, Yi H-J, Hwang K-C, Matsuyama T, Yui K, Im S-H. A distal cis-regulatory element, CNS-9, controls NFAT1 and IRF4-mediated IL-10 gene activation in T helper cells. Mol Immunol. 46:613-621. 2009.
2008年 業績
  1. Honma K, Kimura D, Tominaga N, Miyakoda M, Matsuyama T, Yui K. Interferon regulatory factor-4 differentially regulates the production of Th2 cytokine in naïve vs. effector/memory CD4+ T-cells. Proc. Natl. Acad. Sci. USA. 105: 15890-15895. 2008.
  2. Miyakoda M, Kimura D, Yuda M, Chinzei Y, Shibata Y, Honma K, Yui K. Malaria-specific and non-specific activation of CD8+ T-cells during infection with Plasmodium berghei . J. Immunol. 181(2):1420-1428. 2008.
  3. Yamano T, Sugahara H, Mizukami S, Murata S, Chiba T, Tanaka K, Yui K, Udono H. Allele-selective effect of PA28 in MHC class I antigen processing. J. Immunol. 181(3):1655-1664. 2008.
  4. Mizukami S, Kajiwara C, Ishikawa H, Katayama I, Yui K, Udono H. Both CD4+ and CD8+ T cell epitopes fused to heat shock cognate protein 70 (hsc70) can function to eradicate tumors. Cancer Science. 99(5):1008-1015. 2008.
  5. Susumu S, Nagata Y, Ito S, Matsuo M, Valmori D, Yui K, Udono H, Kanematsu T. Cross-presentation of NY-ESO-1 cytotoxic T lymphocyte epitope fused to human heat shock cognate protein 70 by dendritic cells. Cancer Science. 99(1):107-112. 2008.