Department of
Surgery I
Representative:
Professor Takeshi Nagayasu
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Research fields： Surgical Oncology. Transplantation and Regeneration. Medical Engineering. Laboratory mission: Our laboratory has been established to carry out basic and translational research in surgical oncology and organ transplantation using animal models and regenerated organs. Surgical Oncology: Basic research ・ Signal pathways in cancer cell lines; regulation of epidermal growth factor signals and 5-FU related enzymes ・ Radiation sensitizer for human malignant mesothelioma, pancreatic cancer, and sarcoma Translational research ・ Semi-dry dot blot (SDB) method, a novel diagnostic procedure for determining metastasis to lymph nodes ・ Prognostic and predictive markers Transplantation and Regeneration: Lung Transplantation ・ Preventing ischemia reperfusion injury ・ Immunomodulatory role of adipogenic stromal cells using orthotopic rat lung transplantation models Tissue Engineering ・ Bio-3D-printing technology; scaffold-free cylindrical organs have been created including trachea, esophagus, and intestine ・ Regeneration of the lung and trachea consisted from decellularized scaffolds and epithelial, endothelial and stem cells in rat and swine models Medical Engineering: Medical devices ・ Surgical instruments; endoscopic instruments, devices to assist organ transplantation, bio/nano- materials for prevention of surgical infection. ・ Web site; http://www.mdp.nagasaki-u.ac.jp/hybrid/index_e Domestic Network: Tokyo University of Science; Translational Research Center, Research Institute for Science & Technology Nagoya University; FIRST Research Center for Innovative Nanobiodevices, Graduate School of Engineering Saga University; Department of Regenerative Medicine and Biomedical Engineering Faculty of Medicine Global Network: Yale University; Department of Anesthesia and Biomedical Engineering, New Haven, USA Columbia University Medical Center; Columbia Center for Translational Immunology, New York, USA Cincinnati Children’s Hospital Medical Center; Perinatal Institute, Divisions of Neonatology, Cincinnati, OH, USA Leiden University; Department of Surgery, K6-R Leiden University Medical Center, Leiden, The Netherlands Delft University; Department of Bio-Mechanical Engineering, Delft, The Netherlands |
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http://www.mdp.nagasaki-u.ac.jp/hybrid/index_e.html
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