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Publication 2008
  1. Seki M, Higashiyama Y, Imamura Y, Nakamura S, Kurihara S, Izumikawa K, Kakeya H, Yamamoto Y, Yanagihara K, Tashiro T, Kohno S. A clinical comparative study of piperacillin and sulbactam/ampicillin in patients with community-acquired bacterial pneumonia. Intern Med 48:49-55,2008
  2. Seki M, Suyama N, Hashiguchi K, Hara A, Kosai K, Yanagihara K, Nakamura S, Kurihara S, Imamura Y, Izumikawa K, Kakeya H, Yamamoto Y, Mukae H, Tashiro T, Kohno S. A patient with fulminant influenza-related bacterial pneumonia due to Streptococcus pneumoniae followed by Mycobacterium tuberculosis infection Intern Med 47:2043-2047,2008
  3. Kosai K, Seki M, Yanagihara K, Nakamura S, Kurihara S, Imamura Y, Izumikawa K, Kakeya H, Yamamoto Y, Tashiro T, Kohno S. Two-dimensional gel electrophoresis analysis in simultaneous influenza pneumonia and bacterial infection in mice. Clin Exp Immunol. 152:364-371,2008
  4. Morinaga Y, Yanagihara K, Nakamura S, Yamamoto K, Izumikawa K, Seki M, Kakeya H, Yamamoto Y, Yamada Y, Kohno S, Kamihira S. In vivo efficacy and pharmacokinetics of tomopenem（CS-023）, a novel carbapenem, against Pseudomonas aeruginosa in a murine chronic respiratory tract infection model. J Antimicrob Chemother 62:1326-1331,2008
  5. Yanagihara K, Ohnishi Y, Morinaga Y, Nakamura S, Kurihara S, Seki M, Izumikawa K, Kakeya H, Yamamoto Y, Yamada Y, Kamihira S, Kohno S. Efficacy of ME1036 against methicillin-resistant Staphylococcus aureus and vancomycin-insensitive S. aureus in a model of hematogenous pulmonary infection. Int J Antimicrob Agents 32:401-404,2008
  6. Kosai K, Seki M, Yanagihara K, Nakamura S, Kurihara S, Izumikawa K, Kakeya H, Yamamoto Y, Tashiro T, Kohno S: Elevated levels of high mobility group box chromosomal protein-1（HMGB-1）in sera from patients with severe bacterial pneumonia coinfected with influenza virus. Scand J Infect Dis 40:338-342,2008
  7. Kosai K, Seki M, Yanagihara K, Nakamura S, Kurihara S, Izumikawa K, Kakeya H, Yamamoto Y, Tashiro T, Kohno S: Gabexate mesilate suppresses influenza pneumonia in mice through inhibition of cytokines. J Int Med Res 36:322-328,2008
  8. Kakeya H, Miyazaki Y, Senda H, Kobayashi T, Seki M, Izumikawa K, Yamamoto Y, Yanagihara K, Tashiro T, Kohno S: Efficacy of SPK-843, a novel polyene antifungal, in a murine model of systemic cryptococcosis. Antimicrob Agents Chemother. 52:1871-1872,2008
  9. Kakeya H, Miyazaki Y, Kobayashi T, Seki M, Izumikawa K, Yanagihara K, Yamamoto Y, Tashiro T, Kohno S: Efficacy of SPK-843, a novel polyene antifungal, in comparison with amphotericin B, liposomal amphotericin B, and micafungin against murine pulmonary aspergillosis. Antimicrob Agents Chemother. 52:1868-1870,2008
  10. Kakeya H, Ehara N, Fukushima K, Seki M, Izumikawa K, Yamamoto Y, Yanagihara K, Saito A, Kohno S: Severe legionnaires' disease successfully treated using a combination of fluoroquinolone, erythromycin, corticosteroid, and sivelestat. Intern Med 47:773-777,2008
  11. Yanagihara K, Morinaga Y, Nakamura S, Seki M, Izumikawa K, Kakeya H, Yamamoto Y, Kohno S: Subinhibitory concentrations of telithromycin, clarithromycin and azithromycin reduce methicillion-resistant Staphylococcus aureus coagulase in vitro and in vivo. J Antimicrob Chemother 61:647-650,2008
  12. Kihara R, Yanagihara K, Morinaga Y, Araki N, Nakamura S, Seki M, Izumikawa K, Kakeya H, Yamamoto Y, Tsukamoto K, Kamihira S, Kohno S: Potency of SMP-601, a novel carbapenem, in hematogenous murine bronchopneumonia caused by methicillin-resistant and vancomycin-intermediate Staphylococcus aureus. Antimicrob Agents Chemother 52:2163-2168,2008
  13. Hirakata Y, Yanagihara K, Kurihara S, Izumikawa K, Seki M, Miyazaki Y, Kohno S: Comparison of usefulness of plasma procalcitonin and C-reactive protein measurements for estimation of severity in adults with community-acquired pneumonia. Diagn Microbiol Infect Dis 61:170-174,2008
  14. Tashiro M, Izumikawa K, Yoshioka D, Nakamura S, Kurihara S, Sakamoto N, Seki M, Kakeya H, Yamamoto Y, Yanagihara K, Mukae H, Hayashi T, Fukushima K, Tashiro T, Kohno S: Lung fibrosis 10 years after cessation of bleomycin therapy. Tohoku J Exp Med 216:77-80,2008
  15. Yamamoto Y, Shioshita K, Takazono T, Seki M, Izumikawa K, Kakeya H, Yanagihara K, Tashiro T, Otsuka Y, Ohkusu K, Kohno S: An autopsy case of Erysipelothrix rhusiopathiae endocarditis. Intern Med 47:1437-1440,2008
  16. Saijo T, Izumikawa K, Takazono T, Kosai K, Kurihara S, Nakamura S, Imamura Y, Miyazaki T, Seki M, Kakeya H, Yamamoto Y, Yanagihara K, Miyazaki Y, Fukushima K, Kohno S: A case of Legionella pneumophila pneumonia followed by invasive aspergillosis. Jpn J Infect Dis 61:379-381,2008
  17. Izumikawa K, Zhao Y, Motoshima K, Takazono T, Saijo T, Kurihara S, Nakamura S, Miyazaki T, Seki M, Kakeya H, Yamamoto Y, Yanagihara K, Miyazaki Y, Hayashi T, Kohno S: A case of pulmonary cryptococcosis followed by pleuritis in an apparently immunocompetent patient during fluconazole treatment. Med Mycol 46:595-599,2008
  18. Nakamura S, Higashiyama Y, Izumikawa K, Seki M, Kakeya H, Yamamoto Y, Yanagihara K, Miyazaki Y, Mizuta Y, Kohno S: The roles of the quorum-sensing system in the release of extracellular DNA, lipopolysaccharide, and membrane vesicles from Pseudomonas aeruginosa. Jpn J Infect Dis 61:375-378,2008
  19. Nakamura S, Izumikawa K, Seki M, Kakeya H, Yamamoto Y, Yanagihara K, Miyazaki Y, Kohno S: Pulmonary Cryptococcosis in Late Pregnancy and Review of Published Literature. Mycopathologia 167:125-131,2008
  20. Nakamura S, Yanagihara K, Izumikawa K, Seki M, Kakeya H, Yamamoto Y, Kohno S: A 52-year-old male with Fever and rapidly progressive dyspnea. Respiration 76:454-457,2008
  21. Nakamura S, Yanagihara K, Izumikawa K, Seki M, Kakeya H, Yamamoto Y, Miyazaki Y, Suyama N, Kohno S: Severe pulmonary tuberculosis complicating Ileocecal intussusception due to intestinal tuberculosis: a case report. Ann Clin Microbiol Antimicrob 7:16,2008
  22. Nakamura S, Izumikawa K, Seki M, Fujimoto K, Mishima K, Kakeya H, Yamamoto Y, Yanagihara K, Mizuta Y, Kitaoka T, Kohno S: Reversible visual disturbance due to cryptococcal uveitis in a non-HIV individual. Med Mycol 46: 367-70,2008
  23. Nakamura S, Yanagihara K, Izumikawa K, Seki M, Kakeya H, Yamamoto Y, Soejima Y, Mizuta Y, Kohno S. Systemic metastatic infection and multiple brain abscesses due to severe Klebsiella pneumoniae infection in a 61-year-old male: A case report. IMEID 1:CS1-4,2009

(Presentations)

  1. ATS 2008 Kohno S, Izumikawa K, Akamatsu S, Kageyama A, Takayanagi N, Nakamura S, Inoue Y, Higashiyama Y, Fukushima K, Ishida T,  Sawai T, Yoshimura K, Nakahama C, Omichi M, Kakukawa T, Nishioka Y, Aoki N, Seki M, Kakeya H, Yamamoto Y, Yanagihara K: Evaluation of a rapid immunochromatographic ODK0501 assay for detecting Streptococcus pneumoniae antigens in sputum from patients with lower respiratory tract infection
  2. 17th International Congress for Tropical Medicine and Malaria Kakeya H, Yamamoto Y, Saijo T, Izumikawa K, Seki M, Yanagihara K, Kohno S: Case report: The severe Plasmodium falciparum malaria with acute renal failure and pancreatitis
  3. 48th Interscience Conference on Antimicrobial Agents and Chemotherapy Washington DC Yanagihara K,  Morinaga Y, Araki N, Nakamura S, Izumikawa K, Seki M, Kakeya H, Yamamoto Y, Kamihira S, Kohno S: In vivo efficacy of sivelestat in combination with pazufloxacin against legionella pneumphila in a murine pneumonia model
  4. 48th Interscience Conference on Antimicrobial Agents and Chemotherapy Washington DC Yanagihara K,  Araki N, Morinaga Y, Nakamura S, Seki M, Izumikawa K,  Kakeya H, Yamamoto Y, Kamihira S, Kohno S: In vivo efficacy of doripenem（s-4661）, a novel carbapenem, against Pseudomonas aeruginosa in a murine chronic respiratory tract infection model
  5. 11th Western Pacific Congress on Chemotherapy and Infectious Diseases 2008 Nakamura S, Yanagihara K, Morinaga Y, Izumikawa K, Seki M, Kakeya H, Yamamoto Y, and Kohno S: In vitro activity of sitafloxacin against Haemophilus influenzae including clinical isolates of fluoroquinolone-resisitant strains, and comparison of its mutant prevention concentration to levofloxacin, garenoxacin and ciprofloxacin
  6. 108th General Meeting of the American Society for Microbiology Nakamura S, Yanagihara K, Morinaga Y, Izumikawa K, Seki M, Kakeya H, Yamamoto Y, Kohno S: Clinical Impact of Multiplex Real-time PCR for Rapid Detection of β-lactamase negative ampicillin resistant Haemophilus influenzae（BLNAR）
  7. 108th General Meeting of the American Society for Microbiology Takazono T, Izumikawa K, Kosai K, Saijo T, Nakamura S, Kurihara S, Yamamoto K, Kobayashi T, Imamura Y, Miyazaki T, Seki M, Kakeya H, Yamamoto Y, Yanagihara K, Tashiro T, Kohn S: Analysis of pseudo-positive factors of PlateliaTM Aspergillus galactomannan antigen detection kit in respiratory tract infection patients
  8. 108th General Meeting of the American Society for Microbiology K. Yamamoto, K. Yanagihara, Y. Morinaga, K. Izumikawa, M. Seki, H. Kakeya, Y. Yamamoto, S. Kamihira, S. Kohno: In vitro Activitiy of Garenoxacin against Streptococcus pneumoniae Mutants with Characterized Resistance Mechanisms
  9. Pacific Rim Airway Mucus Symposium, 2008 Morinaga Y, Yanagihara K, Miyashita N, Izumikawa K, Seki M, Kakeya H, Yamamoto Y, Yamada Y, Kamihira S, Kohno S: Azithromycin, Clarithromycin and Telithromycin Inhibit MUC5AC Production Induced by Chlamydophila pneumoniae Protein in NCI-H292 Cells
  10. 108th General Meeting of the American Society for Microbiology Morinaga Y, Yanagihara K, Miyashita N, Nakamura S, Izumikawa K, Seki M, Kakeya H, Yamamoto Y, Yamada Y, Kohno S, Kamihira S: Azithromycin, Clarithromycin and Telithromycin Inhibit MUC5AC Production Induced by Chlamydophila pneumoniae Protein in NCI-H292 Cells
  11. ATS 2008 Seki M, Kosai K, Yanagihara K, Kurihara S, Izumikawa K, Kakeya H, Yamamoto Y, Tashiro T, and Kohno S: Two-dimensional gel electrophoresis analysis in simultaneous influenza pneumonia and bacterial infection in mice
  12. 13th Congress of the Asian Pacific Society of Respirology Hirano K, Kakeya H, Mihara T, Yamamoto K, Imamura Y, Seki M, Izumikawa K, Yanagihara K, Yamamoto Y, Mine M, Tashiro T, Kohno S: The Clinical Feature of Pulmonary Cryptococcosis without HIV Infection in Nagasaki
  13. 13th Congress of the Asian Pacific Society of Respirology Iwanaga N, Yamamoto K, Minematsu A, Hirano K, Imamura Y, Izumikawa K, Seki M, Kakeya H, Yamamoto Y, Yanagihara K, Kohno S: Use of Quanti FERON TB-2G Test for the Diagnosis of Tuberculosis Infection in Nagasaki University Hospital.