Division of Microbiology and Oral Infection     >> Porphyromonas gingivalis is a Gram-negative anaerobic bacterium that is classified in the genus Porphyromonas, family Porphyromonadaceae, order Bacteroidales, class Bacteroides, phylum Bacteroidetes. P. gingivalis had been called Bacteroides melaninogenicus, Bacteroides asaccharolyticus, or Bacteroides gingivalis until 1988. It is a major periodontal pathogen which is often found in deep periodontal pockets of humans. Recently, a number of epidemiological studies have shown significant relationships between periodontal diseases and cardiovascular diseases. P. gingivalis has frequently been found in atherosclerotic plaques. P. gingivalis makes black pigment colonies on the blood agar plates and produces a broad array of potential virulence factors involved in tissue colonization and destruction as well as host defense perturbation. 1. Molecular genetic study of virulence factors in periodontal pathogen, Porphyromonas gingivalis. 2. Study of a link between periodontal infections and increased risk of atherosclerosis and related cardiovascular and cerebrovascular events in human subjects. 3. Study of a link between periodontal infections and bone metabolism. 4. Study of Type IX secretion system that we found in periodontal pathogen, Porphyromonas gingivalis. Position Name Nota Bene Professor     Associate Professor Mariko Naito   Assistant Professor Mikio Shoji   Assistant Professor Keiko Sato   Research Assistant Hideharu Yukitake   1-7-1 Sakamoto, Nagasaki 852-8588, Japan TEL: +81-95-819-7649 FAX: +81-95-819-7650 Our web site   http://www.de.nagasaki-u.ac.jp/en/research/dept_moi_e.html Copyright© 2004-2018 Department of Molecular Microbiology and Immunology, Nagasaki University Graduate School of Biomedical Sciences All Rights Reserved.

Since 2008.02.25