長崎大学医学部 解剖学第一教室

論文 / 業績

 
 
2018
1.
  • Matsumoto G,Inobe T,Amano T,Murai K,Nukina N,Mori N.
  • N-Acyldopamine induces aggresome formation without proteasome inhibition and enhances protein aggregation via p62/SQSTM1 expression.

  • Sci Rep. 2018 Jun 25;8(1):9585.doi: 10.1038/s41598-018-27872-6.
2.
  • Matsumoto G,Matsumoto K,Kimura T,Suhara T,Higuchi M,Sahara N,Mori N.
  • Tau Fibril Formation in Cultured Cells Compatible with a Mouse Model of Tauopathy.

  • int J Mol Sci.2018 May 17;19(5).pii:E1497.doi:10.3390/ijms19051497.
3.
  • 松本弦 森望
  • 超解像蛍光顕微鏡でみるアグリファジーと凝集化タウ
  • Dementia Japan 第32巻 第1号 2018 P.2-11
 
2016
1.
2015
1.
2.
3.
 
2014
1.
2.
3.
  • 松本 弦
  • マイトファジーの認識機構―選択的オートファジーの一形態として.

  • 医学のあゆみ 250, 489-494, 2014
2013
1.
2.
 
2012
1.
2.
3.
4.
 
2011
1.
2.
  • Pearson CA, Ohyama K, Manning L, Aghamohammadzadeh S, Sang H and Placzek M.
  • FGF-dependent midline-derived progenitor cells in hypothalamic infundibular development. Development

  • Development, 138: 2613-2624, 2011
3.
  • Xenaki, D., Martin, I.B., Yoshida, L., Ohyama, K., Gennarini, G., Grumet, M., Sakurai, T. and Furley A.J.W.
  • F3/contactin and TAG1 play antagonistic roles in the regulation of sonic hedgehog-induced cerebellar granule neuron progenitor proliferation.

  • Development, 138: 519-529, 2011
4.
  • Yamagishi N, Yokota M, Yasuda K, Saito Y, Nagata K and Hatayama T.
  • Characterization of stress sensitivity and chaperone activity of Hsp105 in mammalian cells.

  • Biochem. Biophys. Res. Commun. 409 (1): 90-95, 2011
5.
6.
7.
  • 森 望、柿澤 昌
  • 老化脳

  • Clinical Neuroscience(月刊 臨床神経科学)「Neuroplasticity:脳は実は柔らかい」29(7): 811-815, 2011
 
2010
1.
  • Yamaza H, Komatsu T, Wakita S, Kijogi C, Park S, Hayashi H, Chiba T, Mori R, Furuyama T, Mori N and Shimokawa I.
  • Foxo1 is involved in the antineoplastic effect of calorie restriction.

  • Aging Cell. 9 (3): 372-82, 2010
2.
  • Jeon CY, Kim HJ, Morii H, Mori N, Settleman J, Lee JY, Kim J, Kim SC and Park JB.
  • Neurite outgrowth from PC12 cells by basic fibroblast growth factor (bFGF) is mediated by RhoA inactivation through p190RhoGAP and ARAP3.

  • J. Cell Physiol. 224 (3): 786-794, 2010
3.
  • Okamoto A, Koike M, Yasuda K and Kakizuka A.
  • Maintaining ATP levels via the suppression of PERK-mediated rRNA synthesis at ER stress.

  • Biochem. Biophys. Res. Commun. 394 (1): 42-47, 2010
4.
  • 森 望
  • 脳の中の寿命遺伝子.

  • 理大科学フォーラム 312: 7-13, 2010
5.
  • 森 望
  • 神経系の加齢変化、「新老年学(第3版)」大内、秋山、折茂(編)

  • 東京大学出版会 113-154, 2010
 
2009
1.
  • Shiraishi-Yamaguchi Y, Sato Y, Sakai R, Mizutani A, Knopfel T, Mori N, Mikoshiba K and Furuichi T.
  • Interaction of Cupidin/Homer2 with two actin cytoskeletal regulators, Cdc42 small GTPase and Drebrin, in dendritic spines.

  • BMC Neuroscience 10: 25, 2009
2.
  • Hara D, Fukuchi M, Miyashita T, Tabuchi A, Takasaki I, Naruse Y, Mori N, Kondo T and Tsuda M.
  • Remote control of activity-dependent BDNF gene promoter-I transcription mediated by REST/NRSF.

  • Biochem. Biophys. Res. Commun. 384 (4): 506-511, 2009
3.
  • Chiho Mori-Konya, Naruyoshi Kato, Ryota Maeda, Kunihiko Yasuda, Naoki Higashimae, Masakatsu Noguchi, Masaaki Koike, Yoko Kimura, Hiroshi Ohizumi, Seiji Hori and Akira Kakizuka.
  • p97/valosin-containing protein (VCP) is highly modulated by phosphorylation and acetylation.

  • Genes to Cells 14: 483-497, 2009
4.
  • Shimokawa I, Park SC, Mori N and Hwang ES.
  • Japan-Korea Joint Seminar: Asian Aging Core for Longevity 2008 in Nagasaki - Toward the establishment of an Asian Aging Research and Education Center - September 4th to 6th, 2008 at Huis Ten Bosch, Nagasaki, Japan.

  • Mech. Ageing Dev. 130 (3): 198-201, 2009
5.
  • Yamazawa T, Kakizawa S, Oyamada H, Murayama T, Sakurai T, Oguchi K and Iino M.
  • Ryanodine receptors mediate nitric oxide-induced calcium release from intracellular stores.

  • J. Pharmacol. Sci. 105 Suppl 1: 2009
6.
  • 森 望
  • 未病からの老化制御~生理的老化と病的老化の狭間にみる食養と抗加齢サプリ.

  • 未病と抗老化18(1):19-23, 2009
7.
  • 柿澤 昌
  • 中枢ニューロンにおける受容体アダプター分子によるイオン輸送体機能制御と生理学的意義.

  • トランスポーター研究会第3回九州部会要旨集: p20, 2009
 
2008
1.
  • Wang T, Wang Y, Kontani Y, Kobayashi Y, Sato Y, Mori N and Yamashita H.
  • Evodiamine improves diet-induced obesity in a UCP1-independent manner: Involvement of anti-adipogenic mechanism and ERK/MAPK signaling.

  • Endocrinology 149 (1): 358-366, 2008
2.
  • Yamashita H, Wang Y, Kimura K, Inokuma K, Saito M, Kontani Y, Kobayashi Y and Mori N.
  • Impaired basal thermal homeostasis in rats lacking capsaicin-sensitive peripheral small sensory neurons.

  • J. Biochem. 143 (3): 385-393, 2008
3.
  • Mitomo S, Maesawa C, Ogasawara S, Iwaya T, Shibazaki M, Yashima- Abo A, Kotani K, Oikawa H, Sakurai E, Izutsu N, Kato K, Komatsu H, Ikeda K, Wakabayashi G and Masuda T.
  • Downregulation of miR-138 is associated with overexpression of human telomerase reverse transcriptase protein in human anaplastic thyroid carcinoma cell lines.

  • Cancer Sci. 99 (2): 280-286, 2008
4.
  • Izutsu N, Maesawa C, Shibazaki M, Oikawa H, Shoji T, Sugiyama T and Masuda T.
  • Epigenetic modification is involved in aberrant expression of class III beta-tubulin, TUBB3, in ovarian cancer cells.

  • Int. J. Oncol. 32 (6): 1227-1235, 2008
5.
  • Kakizawa S, Moriguchi S, Ikeda A, Iino M and Takeshima H.
  • Functional crosstalk between cell-surface and intracellular channels mediated by junctophilins essential for neuronal functions. (Invited review)

  • Cerebellum 7 (3): 385-391, 2008
6.
  • Zhang P, Ikejima T and Mori N.
  • Regulatory effects of Shc-related phosphotyrosine adaptor proteins on aging.

  • Acta Pharmaceutica Sinica 43 (8): 793-800, 2008 (in Chinese)
7.
  • 森 望
  • 晩年のBenzer研究室の動向からみるショウジョウバエの分子老年遺伝学.

  • 基礎老化研究 32 (3) :1-5, 2008
8.
  • 森 望
  • 分子遺伝学の巨匠 Seymour Benzer--Methuselahの夢と足跡

  • 実験医学 26(5月号)1271-1276, 2008
 
2007
1.
  • Miyashita T, Tatsumi H, Hayakawa K, Mori N and Sokabe M.
  • Large Na(+) influx and high Na(+), K (+)-ATPase activity in mitochondria-rich epithelial cells of the inner ear endolymphatic sac.

  • Pflugers Arch 453 (6): 905-913, 2007
2.
  • Nagai J, Kurokawa M, Takeshima H, Kieffer BL and Ueda H.
  • Circadian-dependent learning and memory enhancement in nociceptin receptor-deficient mice with a novel KUROBOX apparatus using stress-free positive cue task.

  • J. Pharmacol. Exp. Ther. 321 (1): 195-201, 2007
3.
  • Chen L, Miyamoto Y, Furuya K, Mori N and Sokabe M.
  • PREGS induces LTP in the hippocampal dentate gyrus of adult rats via the tyrosine phosphorylation of NR2B coupled to ERK/CREB [corrected] signaling.

  • J. Neurophysiol. 98 (3): 1538-1548, 2007
4.
  • Akita S, Akino K, Yakabe A, Imaizumi T, Tanaka K, Anraku K, Yano H and Hirano A.
  • Combined surgical excision and radiation therapy for keloid treatment.

  • J. Craniofac. Surg. 18 (5): 1164-1169, 2007
5.
  • Imaizumi T, Akita S, Akino K and Hirano A.
  • Acceleration of sensory neural regeneration and wound healing with human mesenchymal stem cells in immunodeficient rats.

  • Stem Cells 25 (11): 2956-2963, 2007
6.
  • 森 望,大神和子
  • 老化・神経変性における神経系の再生・分化のメカニズム

  • Cognition and Dementia特集「神経変性疾患の神経再生・神経移植」(メディカルレビュー社)6 (1):9-17, 2007
7.
  • 森 望
  • 寿命の進化史と遺伝子

  • エコソフィア(昭和堂)19:17-24, 2007
 
2006
1.
  • Watanabe H, Mizutani T, Haraguchi T, Yamaichi N, Minoguchi S, Yamaichi M, Mori N Kameda T, Sugiyama T and Iba H.
  • SWI/SNF complex is essential for NRSF-mediated suppression of neuronal genes in human non-small cell lung carcinoma cell lines.

  • Oncogene 25(3): 47, 2006
2.
  • Imamura K, Morii H, Nakadate K, Yamada T, Mataga N, Watanabe Y and Mori N.
  • Brain-derived neurotrophic factor enhances expression of SCG10 in lateral geniculate nucleus and visual cortex of developing kittens.

  • Eur. J. Neurosci. 23(3): 637-648, 2006
3.
  • Akita S, Akino K, Ren SG, Melmed S, Imaizumi T and Hirano A.
  • Elevated circulating leukemia inhibitory factor in patients with extensive burns.

  • J. Burn Care Res. 27(2): 221-225, 2006
4.
  • Nakanishi K, Ida M, Suzuki H, Kitano C, Yamamoto A, Mori N, Araki M and Taketani S.
  • Molecular characterization of a transport vesicle protein Neurensin-2, a homologue of Neurensin-1, expressed in neural cells.

  • Brain Res. 1081(1): 1-8, 2006
5.
  • Morii H, Yamada T, Nakano I, Coulson JM and Mori N.
  • Site-specific phosphorylation of SCG10 in neuronal plasticity: role of Ser73 phosphorylation by N-methyl D-aspartic acid receptor activation in rat hippocampus.

  • Neurosci. Lett. 396(3): 241-246, 2006
6.
  • Akino K, Mineda T, Mori N, Hirano A, Imaizumi T and Akita S.
  • Attenuation of cysteinyl leukotrienes induces human mesenchymal stem cell differentiation.

  • Wound Repair Regen 14(3): 343-349, 2006
7.
  • Akita S, Akino K, Imaizumi T, Tanaka K, Anraku K, Yano H and Hirano A.
  • The quality of pediatric burn scars is improved by early administration of basic fibroblast growth factor.

  • J. Burn Care Res. 27(3): 333-338, 2006
8.
  • Wang Y, Kimura K, Inokuma K, Saito M, Kontani Y, Kobayashi Y, Mori N and Yamashita H.
  • Potential contribution of vasoconstriction to suppression of heat loss and homeothermic regulation in UCP1-deficient mice.

  • Pflugers Arch 452(3): 363-369, 2006
9.
  • Akita S, Akino K, Imaizumi T, Tanaka K, Anraku K, Yano H and Hirano A.
  • A polyurethane dressing is beneficial for split-thickness skin-graft donor wound healing.

  • Burns 32(4): 447-451, 2006
10.
  • Akita S, Akino K, Tanaka K, Anraku K, Yano H and Hirano A.
  • Therapeutic choice for craniofacial venous malformations.

  • J. Craniofac. Surg. 17(4): 729-735, 2006
11.
  • Morii H, Shiraishi-Yamaguchi Y and Mori N.
  • SCG10, a microtubule destabilizing factor, stimulates the neurite outgrowth by modulating microtubule dynamics in rat hippocampal primary cultured neurons.

  • J. Neurobiol. 66: 1101-1114, 2006
12.
  • Chen L, Miyamoto Y, Furuya K, Dai XN, Mori N and Sokabe M.
  • Chronic DHEAS administration facilitates hippocampal long-term potentiation via an amplification of Src-dependent NMDA receptor signaling.

  • Neuropharmacology 51(3): 659-670, 2006
13.
  • 森 望
  • Shcシグナリングからみる寿命制御と老化脳保護.

  • 生化学 78(3): 189-200, 2006
14.
  • 森 望
  • 遺伝子が解き明かす生と死のシナリオ.

  • ニュートン別冊『知っているようで知らない人体の秘密』, 2006
15.
  • 森 望
  • 脳の発達と幼児教育.

  • 教育と医学. 54(4), 58-64, 2006
 
2005
1.
  • Miyamoto Y, Chen L, Sato M, Sokabe M, Nabeshima T, Pawson T, Sakai R and Mori N.
  • Hippocampal synaptic modulation by the phosphotyrosine adapter protein ShcC/N-Shc via interaction with the NMDA receptor.

  • J. Neurosci. 25 (7): 1826-1835, 2005
2.
  • Nakatani T, Ueno S, Mori N and Matsuoka I.
  • Role of NRSF/REST in the molecular mechanisms regulating neural-specific expression of trkC/neurotrophin-3 receptor gene.

  • Brain Res. Mol. Brain Res. 135 (1-2): 249-259, 2005
3.
  • Fukui M, Akita S and Akino K.
  • Ectopic bone formation facilitated by human mesenchymal stem cells and osteogenic cytokines via nutrient vessel injection in a nude rat model.

  • Wound Repair Regen. 13 (3): 332-340, 2005
4.
  • Kontani Y, Wang Y, Kimura K, Inokuma KI, Saito M, Suzuki-Miura T, Wang Z, Sato Y, Mori N and Yamashita H.
  • UCP1 deficiency increases susceptibility to diet-induced obesity with age.

  • Aging Cell 4 (3): 147-155, 2005
5.
  • Nakagawa H, Akita S, Fukui M, Fujii T and Akino K.
  • Human mesenchymal stem cells successfully improve skin-substitute wound healing.

  • Br. J. Dermatol. 153 (1): 29-36, 2005
6.
  • Akino K, Toyota M, Suzuki H, Mita H, Sasaki Y, Ohe-Toyota M, Issa JP, Hinoda Y, Imai K and Tokino T.
  • The Ras effector RASSF2 is a novel tumor-suppressor gene in human colorectal cancer.

  • Gastroenterology 129: 156-169, 2005
7.
  • Akino K, Mineda T and Akita S.
  • Early cellular changes of human mesenchymal stem cells and their interaction with other cells.

  • Wound Repair Regen. 13 (4): 434-440, 2005
8.
  • Mori N
  • Rooting “Ko-ko-ro” into the brain: Toward the neuroanatomy of mind.

  • Acta Medica Nagasakiensia 50: 83-91, 2005
9.
  • Nakazawa T, Morii H, Tamai M and Mori N.
  • Selective up-regulation of RB3/stathmin4 by ciliary neurotrophic factor following optic nerve axotomy.

  • Brain Res. 1061 (2): 97-106, 2005
10.
  • 10.Akita S, Akino K, Imaizumi T and Hirano A.
  • A basic fibroblast growth factor improved the quality of skin grafting in burn patients.

  • Burns 31 (7): 855-858, 2005
11.
  • 1Akino K, Akita S, Mizuguchi T, Takumi I, Yu R, Wang XY, Rozga J, Demetriou AA, Melmed S, Ohtsuru A and Yamashita S.
  • A novel molecular marker of pituitary tumor transforming gene involves in a rat liver regeneration.

  • J. Surg. Res. 129 (1): 142-146, 2005
12.
  • Nomura M, Uda-Tochio H, Murai K, Mori N and Nishimura Y.
  • The neural repressor NRSF/REST binds the PAH1 domain of the Sin3 corepressor by using its distinct short hydrophobic helix.

  • J. Mol. Biol. 354 (4): 903-915, 2005
13.
  • Nakazawa T, Shimura M, Endo S, Takahashi H, Mori N and Tamai M.
  • N-Methyl-D-Aspartic acid suppresses Akt activity through protein phosphatase in retinal ganglion cells.

  • Mol. Vis. 11: 1173-1182, 2005
14.
  • Akita S, Fukui M, Fujii T and Akino K.
  • Interaction between mesenchymal stem cells and osteogenic cytokines in vitro and in vivo. The status of new technology in tissue repair at the beginning of the 21st century.

  • In European Tissue repair Society Bulletin, Vol 12, (Cherry G ed; Positif Press, Oxford) pp. 78-79, 2005
15.
  • 森 望
  • 老化とシグナル伝達:食物栄養調節の視点から

  • 老年消化器病 16, 209-215, 2005
16.
  • 森 望、Mahendra S Rao、大神和子
  • 老化脳における神経再生

  • 基礎老化研究 29, 41-51, 2005
17.
  • 森 望
  • 神経シグナルと神経精神疾患

  • 実験医学【増刊:シグナル伝達研究2005】23, 230-239, 2005
18.
  • 黒川 衛
  • マウスカラーアトラスと写真で見る脳実験マニュアル
  • 羊土社, 2005
 
2004
1.
  • Nakao C, Itoh TJ, Hotani H and Mori N.
  • Modulation of the stathmin-like microtubule destabilizing activity of RB3, a neural-specific member of the SCG10 family, by its N-terminal domain.

  • J. Biol. Chem. 279 (22) 23014-23021, 2004
2.
  • Murai K, Naruse Y, Shaul Y, Agata K and Mori N.
  • Direct interaction of NRSF with TBP: The chromatin-reorganization and the core promoter repression for neuron-specific gene transcription.

  • Nuc. Acids Res. 32 (10) 3180-3189, 2004
3.
  • Furuyama T, Kitayama K, Shimoda Y, Ogawa M, Sone K, Yoshida-Araki K, Hisatsune H, Nishikawa SI, Nakayama K, Nakayama K, Ikeda K, Motoyama N and Mori N.
  • Abnormal angiogenesis in Foxo1 (FKHR) -deficient mice.

  • J. Biol. Chem. 279 (33) 34741-34749, 2004
4.
  • Ida M, Suzuki H, Mori N, Taketani S and Araki M.
  • Neuro-p24 plays an essential role in neuriteextension: antisense oligonucleotide inhibition of neurite extension in cultured DRG neurons and neuroblastoma cells.

  • Neurosci. Res. 50 (2) 199-208, 2004
5.
  • Sugawara H, Inoue K, Iwata S, Shimizu T, Yamada K, Mori N and Miyata, A.
  • Neural-restrictive silencers in the regulatory mechanism of pituitary adenylate cyclase-activating polypeptide gene expression.

  • Regulatory Peptides 123 (1-3) 9-14, 2004
6.
  • Hanada R, Teranishi H, Pearson J T, Kurokawa M, Hosoda H, Fukushima N, Fukue Y, Serino R, Fujihara H, Ueta Y, Ikawa M, Okabe M, Murakami N, Shirai M, Yoshimatsu H, Kangawa K and Kojima M.
  • Neuromedin U has a novel anorexigenic effect independent of the leptin signaling pathway.

  • Nat Med. 10 (10) 1067-1073, 2004
7.
  • Hara M, Saikawa T, Kurokawa M, Sakata T and Yoshimatsu H.
  • Leg fat percentage correlates negatively with coronary atherosclerosis.

  • Circ. J. 68 (12) 1173-1178, 2004
8.
  • Akita S, Daian T, Ishihara H, Fujii T and Akino K.
  • Leukemia inhibitory factor-transfected embryonic fibroblasts and vascular endothelial growth factor successfully improve the skin substitute wound healing by increasing angiogenesis and matrix production.

  • J. Dermatol. Sci. 36 (1) 11-23, 2004
9.
  • Akita S, Fukui M, Nakagawa H, Fujii T and Akino K.
  • Cranial bone defect healing is accelerated by mesenchymal stem cells induced by coadministration of bone morphogenetic protein-2 and basic fibroblast growth factor.

  • Wound Repair Regen. 12 (2) 252-259, 2004
10.
  • 森 望
  • 老化遺伝子

  • 臨床整形外科(医学書院)39 (2) 176-179, 2004
11.
  • 森 望
  • 脳の老化と寿命制御

  • 日本老年医学会雑誌 41 ( 3 ) 266 -270, 2004
12.
  • 森 望
  • ドッキング蛋白Shcの神経系における役割

  • 生体の科学 55 (2) 103-110, 2004
13.
  • 森 望
  • 生物の生存戦略と寿命制御の遺伝子背景

  • 科学(岩波書店)74 (12) 1398-1402, 2004
 
2003
1.
  • Furuyama T, Kitayama K, Yamashita H and Mori N.
  • Forkhead transcription factor FOXO1 (FKHR)-dependent induction of PDK4 gene expression in skeletal musclesduring energy deprivation.

  • Biochem J. 375: 365-371, 2003
2.
  • Wang Z, Kontani Y, Sato Y, Mizuno T, Mori N and Yamashita H.
  • Muscle type difference in the regulation of UCP3 under cold conditions.

  • Biochem. Biophys. Res. Comm 305 (2): 244-249, 2003
3.
  • Mori N, Zhu W, Sone K, Miyamoto Y, Kadokawa Y, Ihara T and Wakao R.
  • Roles of Shc signaling in oxidative stress response and aging.

  • J. Clin. Biochem. Nutr. 34, 69-76, 2003
4.
  • Sohn SY, Weitzdoerfer R, Mori N and Lubec G.
  • Transcription factor REST dependent proteins are comparable between Down syndrome and control brains: challenging a hypothesis.

  • J. Neural Transm. Suppl. 67, 59-66, 2003
5.
  • Kakizawa S, Yamada K, Iino M, Watanabe M and Kano M.
  • Effects of insulin-like growth factor I on climbing fibre synapse elimination during cerebellar development.

  • Eur. J. Neurosci. 17 (3), 545-554, 2003
6.
  • 大野 翠、須藤鎮世、山口陽子、森 望、早川智
  • 大野乾の世界

  • 羊土社, 2003
7.
  • 森 望
  • 長寿遺伝子の新潮流

  • Medical Practice(文光堂)20 (10) 1796-1797, 2003
8.
  • 森 望、古山達雄、山下 均
  • エネルギー応答、ストレス応答から老化制御へ

  • 日本老年医学会雑誌 40 (6) 578-581, 2003